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SDĚLENÍ341200012656130188244301376409
Z772200012659
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reakce52636001063466108143176208
po75036001063273
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kontaktní137536001063372113146182217251293311
dermatitidě170136001063870106160201229247279297336368
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reakce983920029892217343472575699
po17319200298143281
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MUDr.3401580013793168245287311
Anna6731580013772136200259
Hrazdírová9541580013776118175227294324366430486544
Pediatrická3401730013359111174199251286322347396447500
klinika,864173001335178103163188239293315
FN12031730013353123
Brno1350173001335995156216
a15891730013353
LF16661730013352104
MU17941730013388158
v19761730013353
Brně2052173001336095156211
Idová340224001212482138186235
reakce604224001213383132180224274
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dermatitida)16462240012157108141226275308332365389446495521
je2196224001212576
generalizovaná,23012240012156107164215249298322345389444492541597646668
imunologicky29982240012123107163219275300356413437482529581
podmíněná360722400121581151733402380012183107162212268316
kožní6802380012147100143198221
reakce,925238001213383131177221270290
která1239238001214783132165213
vzniká1476238001214994149172219268
sekundárně1768238001214090137193248305353385441491
na22832380012156104
podkladě24112380012157113170217242290346397
vzdáleného2832238001214893149197220271326377433488
primárního3344238001215790113196244277333356413468
ložiska.340252001212479121144184230280301
Typicky669252001215091149172217264314
se1011252001214091
vyskytuje1130252001214899138185235272327350401
u15592520012155
pacientů16362520012156105150173223279312366
s20312520012139
ekzémem2092252001215097144194278328412
či2532252001214568
mykotickými26282520012184129177231263287331378428513536
a31922520012148
bakteriálními32622520012157105152188238270294342365421444527550
infekcemi340266001212378106156203246294377400
kůže,7582660012146101143193212
avšak988266001214894132181227
v12322660012148
praxi1301266001215689137184207
bývá15262660012156102153201
často1744266001214593132165219
opomíjena19802660012155111167249272297346402449
nebo24462660012156106162217
mylně26812660012183128151206256
diagnostikována.2954266001215679126182237291330363386432485532580635682703
Pro3674266001215385139
úspěšné340280001215594150200239294344
zhojení702280001214398152176226281304
je1024280001212474
zásadní1116280001214292130179235290313
terapie1447280001213382114162219242292
primární1757280001215689112195243275330353
léze2128280001212373116166
a23122800012148
symptomatická2380280001213987171227260314397444477499544590639
léčba3036280001212474119175224
idové3277280001212480135181230
reakce.3525280001213282129176219268288
V3402940012155
kazuistice416294001214795138193215254287310354403
popisujeme8362940012157112168191230284307357440490
případ1343294001215789112168216272
12letého1633294001215194116166199247303357
pacienta20082940012156104148171221276308356
s23812940012140
impetiginizovanou24412940012123105161212245268323346400423465519566614668723777
kontaktní3236294001214699155186235281316371394
dermatitidou364729400121561061383403080012183130162184217239295349404
levého761308001212373119168223277
kolene1055308001214799123172227277
po13493080012156111
traumatu,1478308001213264112166248295327381401
komplikovanou18963080012147100182238262284330383429477531585640
vznikem2553308001214892146169215263345
idové2916308001212378133179227
reakce3161308001213281128174217265
na34433080012155103
trupu,3563308001213364119175229250
krku340322001214680126180
a5383220012147
v6053220012148
axilách.673322001214894118140187231285306
Onemocnění9963220012168123173255310354409458513535
bylo15483220012156102126180
provázeno1745322001215688142188236278328382436
výraznou2198322001214898131178221275330384
periferní25993220012156106139162190240272327349
eozinofilií.29653220012150105146169223277305331354376398419
Vzhledem3401322001215596151174223279329411
k3403360012148
rozsahu410336001213388131173223280336
projevů775336001215791147171222271328
byla11323360012157105130179
indikována1340336001212380137161209264312361417466
kombinovaná18363360012147102187245269325382430479536585
lokální2450336001212480128178202259282
a27613360012149
systémová2832336001214090130165215300356404454
léčba,3315336001212475122179229251
která3595336001214784134168218
vedla340350001214897154178226
k5873500012147
ústupu656350001215594128183239295
primárních973350001215689113196244277332356400455
i14503500012123
sekundárních1494350001214090138193248305353386441465509564
kožních20803500012147100143198221266321
lézí.2422350001212474118141162
Kazuistika26053500012155104147202226265299322368417
podtrhuje30443500012157113170203236291346370420
nutnost34863500012155110143198253293327
včasného340364001214891139177231281336391
rozpoznání748364001213286127184239280335382437459
idové1225364001212379133180228
reakce,1470364001213382129175218267286
adekvátního17733640012148104154200251299331385408464519
mikrobiologického23093640012183105151185239295318373396451507529573619667722777
vyšetření3103364001214898137186219251300355378
a34983640012148
cílené356636400121456792142197246
léčby340378001212372117172217
primárního573378001215688111192239271325347403457
ložiska.1046378001212477118141179224272293
Zároveň13553780012155103134187233281335
upozorňuje17073780012154109164204258290344397420469
na21933780012154101
riziko231137800121325596119164217
záměny2544378001214291172221276320
s28813780012138
lékovým2939378001212372118171217266348
exantémem.3304378001214995142196227275357406488508
Klíčová340395001246292121167226279333
slova:701395001244473133186240267
idová997395001212482138186236
reakce,1262395001213384133181226276296
autosenzitizační15873950012149105139194235286343387411445469513564610666690
dermatitida,23063950012157109142228277310334368392449499520
kontaktní28553950012148103160193243291328384408
dermatitida,32923950012157109143228277311334368392450499521
impetiginizace,3404090012123106163214248271327350405428471521566615634
eozinofilie.9964090012150106147171226281310336360383433453
Id340437001242889
reaction449437001243892145191230258316376
following845437001243492121149207282310369429
impetiginized12944370012427114174228265294353381440468516569630
contact19444370012445103162199253298337
dermatitis23014370012460113152239292329357395423467
An3404540012161117
id485454001212380
reaction593454001213383131176212235290346
(autosensitization967454001212974128162216255306362401424457480523573605629684740
dermatitis)17354540012156107140224272305328361384423448
is2211454001212463
a23024540012149
generalized,23724540012156107163213246295318341384435492513
immunologically29134540012124107190245301356380435492515560609633656703
mediated36454540012183134340468001215680127160209267
skin628468001213986111166
response815468001213282122178234290329379
that1215468001213389137169
develops14054680012156107154203227283340379
secondarily1805468001214090136189245302350382406429477
as2303468001214887
a24114680012148
result2480468001213383122177200233
of2734468001215584
a28394680012149
distant2909468001215679118152201256289
primary3219468001215790113196244277327
focus.3567468001212984130185224245
It340482001212458
typically426482001213484143167212262286309357
occurs8124820012155102146201235276
in1116482001212480
patients12254820012157107140163214270303344
with1598482001217499132188
eczema1815482001215197142193278326
or2170482001215689
fungal2288482001212986142199248271
and25884820012149105162
bacterial27794820012158107152188238272296344368
skin3176482001214087112168
infections,3373482001212480109160206242266321378418439
yet340496001214796130
in495496001212479
clinical59949600121456891146169214263286
practice910496001215790139184219242287336
it1271496001212356
is1353496001212362
often1441496001215484120169225
overlooked16914960012155102151184208263319366415472
or2189496001215487
misdiagnosed.23024960012183106145202225273329384440479529586607
Successful29354960012149104149192241281320350406429
resolution3390496001213282122177201255289312367422
depends3405100012156107164215271327367
on7355100012155111
adequate8745100012148105155212267315348397
treatment1299510001213366116164196280330386418
of1745510001215585
the1858510001213388138
primary2025510001215790113196244277327
lesion2381510001212373113136191247
together2656510001213387144194228283333366
with3050510001217498131186
symptomatic3264510001214088172229262316400448481504548
management3405240012184132188236293343427478534567
of935524001215685
the1049524001213388139
id1217524001212380
reaction.1326524001213383131176212235291347368
We17235240012185133
present1884524001215791141181231287320
the2233524001213388139
case2401524001214594133184
of2614524001215584
a27275240012148
12-year-old2797524001215195125172222270303331389413470
patient32965240012157106139162213269301
with3626524001217498131187
impetiginized3405380012123106163214248271327350405428471521578
contact943538001214599155187236281316
dermatitis12845380012156107140223271304327360383422
of1731538001215584
the1841538001213388138
left2004538001212474104140
knee21705380012146103154205
following2400538001212984108131186259283338394
trauma,2819538001213466115169252301322
complicated3166538001214498182239263286330379411461518
by37095380012157103
the340552001213388139
development5025520012157107155204228283340424474530562
of1088552001215584
an11965520012148103
id1323552001212480
reaction1427552001213383131175211234289345
on17955520012155111
the1930552001213388138
trunk,2092552001213366121177223247
neck23625520012156106152198
and25845520012148104160
axillary2768552001214896119143166214246297
regions.3088552001213383140163218274313334
The34465520012150106156
condition3626552001214599154340566001215680113136191246
was6095660012174122161
accompanied793566001214893136190274330379434457508565
by13805660012157104
peripheral15065660012157108141165221277328360409432
eosinophilia.19615660012150106145168223278335391414438461509530
Owing25135660012169144167223279
to2814566001213387
the2924566001213388138
extent3085566001215097133182238270
of3378566001215584
the3485566001213388138
skin3646566001213986111166
involvement,340580001212379126180204253302386437493525546
a9155800012148
combination985580001214599183240264319367400423479535
of1548580001215585
topical1661580001213388145169214263286
and19765800012148104161
systemic2165580001214088128162212296319364
therapy2558580001213388139172221278325
was29115800012174123162
initiated,3101580001212479103136159207240290347368
leading3498580001212374122179203258315
to340594001213388
regression456594001213383140173223263303326381437
of922594001215584
both10355940012157113146202
the1265594001213389140
primary1433594001215791114198246279330
and17915940012149104161
secondary1981594001214091137191247304352385435
skin2445594001214087112167
lesions.2641594001212474114137193249288309
This29795940012150107130169
case3177594001214594133184
highlights3390594001215679135191214238294349382423
the340608001213490142
importance5116080012124109167224258295345402448498
of1039608001215585
quick11546080012157113137183231
recognition1414608001213384131186244301325359383439496
of1940608001215585
id2055608001212482
reactions,2166608001213384133180216240296353393415
appropriate26106080012149107166200256314348373422455506
microbiological31456080012185109155188244303327383408465523547593643667
assessment340622001214887126177216256338389445477
and8406220012148103160
targeted1022622001213382115170221254303361
treatment1405622001213366116164196279330386418
of1845622001215584
the1952622001213388139
primary2113622001215790113197245277327
focus.2463622001212984130185224245
It2731622001212457
also2810622001214872111166
emphasizes29986220012151134191247295334357400450489
the3510622001213388138
risk367162200121325695142
of340636001215584
misdiagnosis4456360012184107146203226274330385440479502541
as1007636001214988
a11166360012148
drug-induced1185636001215789145201233257312369424469518575
exanthema.1781636001215098146201233289339423471492
Key3406530012461113164
words:5276530012476133171232276302
id852653001212380
reaction,955653001213383131176211234289345366
autosensitization13446530012148103136190229280335374397430453496546579602657712
dermatitis,20806530012156107139223271304327360383422443
contact2546653001214599155187236281316
dermatitis,28856530012157107140224272304327360383423444
impetiginization,33526530012123106163214248271327350405428340667001214393125148203259280
eosinophilia.6416670012150106145168223278335391415438461509530
Úvod3407170014780142208279
Idová480734001092273123166210
reakce712734001092975118161200245
(autosenzitizační979734001092566116146195231276327366388418439478523563613635
dermatitida,1636734001095096126202245275296326347340748001095194114
autoekzematizace)474748001094493123172218261304349425468498519558603644688712
je1206748001092268
sekundární1294748001093682125175225276320350400421
imunologicky1736748001092196146196246340762001092170120141181222266
podmíněná6227620010950100151225245294339388431
kožní1068762001094290127176197
erupce,1280762001094474123173214257275
která1570762001094274118147190
vzniká1775762001094383132152194238
jako340776001092265108157
odpověď5157760010950101153203246291343
na877776001095093
vzdálené989776001094384135179200246296342
primární1350776001095181103178221251302323
ložisko1691776001092272110131167209258
–19677760010945
nejčastěji2140720001095198120162207243275320343365
infekční,2531720001092173100146190231282303323
ekzematózní2880720001094690133180257302332382421472494
(1)340072000109267090
či3516720001094162
stasis3605720001093667113149171207
dermatitis2140734001095196126202246275296327348383
(2,254873400109267189
3).266273400109477087
Mechanismem27747340010972118160210253303325360435481557
je3356734001092267
přehnaná3448734001095282127177227271321365
imunitní2140748001092196146196217247298319
reakce2483748001093075119161201245
organismu2753748001094979130173223245280355405
na3183748001095093
zánět3301748001093884134179210
v35357480010944
jiném359874800109224393139214
místě2140762001097596132163207
kůže,2372762001094293131177195
což2592762001094089127
vede2744762001094388140186
k29547620010943
výsevu3016762001094389125171214264
morfologicky33057620010975125155185234256306358379420462508
odlišných21407760010949100120141176224265304353
kožních2508776001094290127176197237285
projevů2809776001095080128149194236286
mimo3110776001097495168217
původní3343776001095099142190241290311
lézi.3669776001092166104125144
DECLARATIONS:4070226008648871301662142563043393604124625014571226008514
Declaration406924000874987120141179207245272292334376
of445924000874166
originality:45392400087406888131151193231252272299338358
The406925100853473109
manuscript418925100855791130168195227249266306329
is452925100851644
original45842510085386178117133172205222
and481725100853472112
has49402510085387299
not50512510085387699
been516225100853975110149
published532225100854078118135151178217252292
or406926200853862
submitted414626200852867108167184208234269310
elsewhere.44712620085355381117169209246269305320
Ethical406927600873764107127160198219
principles43022760087427090132165185229249288319
compliance:463627600873172134177198218256298331369388
The406928700853678116
authors420628700853475100142183208238
attest44652870085356087124154179
that466528700852465101126
their481228700852465103121146
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by406929800854073
the41592980085236399
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Committee464929800854179139198215239265300337
and500229800853474114
is513329800851745
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compliance526729800853270130170188205239279311347
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welfare512930900855391110133170196233
regulations53913090085236110414516420140693200085234080120148
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authors’44353200085347397136176200229244
institutions46993200085175684109126150189214231270310338
as505732000853462
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World406933100856099124142184
Medical427433100855795137154188224242
Association453633100854474104144178196231256273314355
Declaration491233100854785119136172196232257274315356
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Helsinki537033100854785103132150190225244
on406934200853878
Ethical41663420085345898115147182199
Principles43843420085376178117150167207225261290
for46923420085216084
Medical479534200855693134151183218235
Research504934200853874102139173197229268
Involving53363420085165690128146181198238278
Human406935300854685145179219
Subjects430835300853474114132168201227256
adopted458435300853474114155179215256
by486035300853973
the49533530085236399
18th507235300853669514335300501437
WMA5199353008559116160
General537935300854582122158182217235
Assembly406936400854475105143204247266302
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Helsinki,447536400854785104134152193228248264
Finland,47623640085355394113149190232249
in503436400851758
June511636400852668109147
1964,528636400853771110150166
with54763640085537197138
subsequent406937500852867107136172213252288328352
amendments,443837500853493130169210269305345369398414
as486937500853462
well494937500855287105122
as508937500853362
with51683750085526993133
the53193750085236299
ICMJE543537500851759116143179
Recommendations406938600853977112153216278317359402439465483525568598
for46993860085216389
the481938600852466105
Conduct,495538600854283125168210245272290
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