Dermatol. praxi. 2022;16(1):28-31 | DOI: 10.36290/der.2022.005

Skin manifestations COVID-19

MUDr. Slavomír Urbanček, MUDr. Petra Fedorcová
Dermatovenerologická klinika SZU, FNsP F. D. Roosevelta Banská Bystrica

Viral rashes are well-known group in dermatology. Coronavirus-2 (SARS-CoV-2) pandemy affecting millions of people revealed large spectrum pulmonal and extrapulmonal symptoms. Dermatologic manifestations could be divided into 6 groups: urticarial rash, confluent erythematous/maculopapular/morbilliform rash, papulovesicular exanthem, chilblain-like acral pattern, livedo reticularis/racemosa-like pattern and purpuric "vasculitic" pattern. Paper summarizes current knowledges with respect to incidence, clinical picture a relationship of rashes to the course and severity of COVID-19 infection.

Keywords: COVID-19, viral rash, skin, infection.

Published: April 4, 2022  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Urbanček S, Fedorcová P. Skin manifestations COVID-19. Dermatol. praxi. 2022;16(1):28-31. doi: 10.36290/der.2022.005.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Scott LA, Stone MS. Viral exanthems. Dermatology Online Journal. 2003;9(3):4. Go to original source...
    2. Genovese G, Moltrasio C, Berti E, et al. Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives. Dermatology. 2021;237:1-12. Go to original source... Go to PubMed...
    3. Matar S, Oulès B, Sohier P, et al. Cutaneous manifestationsin SARS-CoV-2 infection (COVID-19): a French experience and a systematic review of the literature. J Eur Acad Dermatol Venereol. 2020;34:e686-e689. Go to original source... Go to PubMed...
    4. Imbalzano E, Casciaro M, Quartuccio S, et al. Association between urticaria and virus infections: A systematic review. Allergy Asthma Proc. 2016;37:18-22. Go to original source... Go to PubMed...
    5. Galván Casas C, Català A, Carretero Hernández G, et al. Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases. Br J Dermatol. 2020;183:71-77. Go to original source... Go to PubMed...
    6. Freeman EE, McMahon DE, Lipoff JB, et al. The spectrum of COVID-19-associated dermatologic manifestations: an international registry of 716 patients from 31 countries. J Am Acad Dermatol. 2020;83:1118-1129. Go to original source... Go to PubMed...
    7. Shanshal M. Low-dose systemic steroids, an emerging therapeutic option for COVID-19-related urticaria. J Dermatolog Treat. 2020;16:1-2. Go to original source... Go to PubMed...
    8. Català A, Galván-Casas C, Carretero-Hernández G, et al. Maculopapular eruptions associated to COVID-19: A subanalysis of the COVID-Piel study [Online ahead of print]. Dermatol Ther (Heidelb). Dermatol Ther. 2020;33:e14170. Go to original source... Go to PubMed...
    9. Najarian DJ. Morbilliform exanthem associated with COVID-19. J Am Acad Ddermatol Case Rep. 2020;6:493-494. Go to original source... Go to PubMed...
    10. Trellu LT, Kaya G, Alberto C, et al. Clinicopathologic Aspects of a Papulovesicular Eruption in a Patient With COVID-19. JAMA Dermatol. 2020;156:922-924. Go to original source... Go to PubMed...
    11. Marzano AV, Genovese G, Fabbrocini G, et al. Varicella-like exanthem as a specific COVID-19-associated skin manifestation: multicenter case series of 22 patients. J Am Acad Dermatol. 2020;83:280-285. Go to original source... Go to PubMed...
    12. Recalcati S. Cutaneous manifestations in COVID-19: a first perspective. J Eur Acad Dermatol Venereol. 2020;34:e212-e213. Go to original source... Go to PubMed...
    13. De Giorgi V, Recalcati S, Jia Z, Chong W, Ding R, Deng Y, et al. Cutaneous manifestations related to coronavirus disease 2019 (COVID-19): A prospective study from China and Italy. J Am Acad Dermatol. 2020;83:674-675. Go to original source... Go to PubMed...
    14. Tammaro A, Adebanjo GA, Parisella FR, et al. Cutaneous manifestations in COVID-19: the experiences of Barcelona and Rome. J Eur Acad Dermatol Venereol. 2020;34:e306-307. Go to original source... Go to PubMed...
    15. Fernandez-Nieto D, Ortega-Quijano D, Jimenez-Cauhe J, Burgos-Blasco P, de Perosanz-Lobo D, Suarez-Valle A, et al. Clinical and histological characterization of vesicular COVID-19 rashes: a prospective study in a tertiary care hospital. Clin Exp Dermatol. 2020;45:872-875. Go to original source... Go to PubMed...
    16. Zhou Z, Ren L, Zhang L, et al. Overly exuberant innate immune response to SARS-CoV-2 infection. SSRN Electronic J. 2020; doi: 10.2139/ssrn.3551623. Go to original source...
    17. Kaya G, Kaya A, Saurat JH. Clinical and Histopathological Features and Potential PathologicalMechanisms of Skin Lesions in COVID-19: review of the Literature. Dermatopathology (Basel). 2020;7:3-16. Go to original source... Go to PubMed...
    18. Piccolo V, Neri I, Filippeschi C, et al. Chilblainlike lesions during COVID-19 epidemic: a preliminary study on 63 patients. J Eur Acad Dermatol Venereol. 2020;4:e291-293. Go to original source... Go to PubMed...
    19. Colmenero I, Santonja C, Alonso-Riaño M, et al. SARS--CoV-2 endothelial infection causes COVID-19 chilblains: histopathological, immunohistochemical and ultrastructural study of seven paediatric cases. Br J Dermatol. 2020;183:729-737. Go to original source... Go to PubMed...
    20. Fernandez-Nieto D, Jimenez-Cauhe J, Suarez-Valle A, et al. Characterization of acute acral skin lesions in nonhospitalized patients: A case series of 132 patients during the COVID-19 outbreak. J Am Acad Dermatol. 2020;83:61-63. Go to original source... Go to PubMed...
    21. Manalo IF, Smith MK, Cheeley J, et al. A dermatologic manifestation of COVID-19: transient livedo reticularis. J Am Acad Dermatol. 2020;83:700. Go to original source... Go to PubMed...
    22. Magro C, Mulvey JJ, Berlin D, Nuovo G, Salvatore S, Harp J, et al. Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases. Transl Res. 2020;220:1-13. Go to original source... Go to PubMed...
    23. Jimenez-Cauhe J, Ortega-Quijano D, Carretero-Barrio I, et al. Erythema multiforme-like eruption in patients with COVID-19 infection: clinical and histological findings. Clin Exp Dermatol. 2020;45:892-895. Go to original source... Go to PubMed...
    24. Dash S, Sirka CS, Mishra S, Viswan P. COVID-19 Vaccine-Induced Stevens-Johnson Syndrome. Clin Exp Dermatol. 2021;46:1615-1617. Go to original source... Go to PubMed...
    25. Ehsani AH, Nasimi M, Bigdelo Z. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection. J Eur Acad Dermatol Venereol. 2020;34(9):e436-e437. doi: 10.1111/jdv.16579. Go to original source... Go to PubMed...
    26. Gupta A, Gill A, Sharma M, Garg M. Multi-System Inflammatory Syndrome in a Child Mimicking Kawasaki Disease. J Trop Pediatr. 2020; fmaa060. doi: 10.1093/tropej/fmaa060. Go to original source... Go to PubMed...
    27. Llamas-Velasco M, Chicharro P, Rodríguez-Jiménez P, et al. Comment on 'Clinical and histological characterization of vesicular COVID-19 rashes: a prospective study in a tertiary care hospital'. Pseudoherpetic Grover disease seems to occur in patients with COVID-19 infection. Clin Exp Dermatol. 2020;45:896-898. Go to original source... Go to PubMed...
    28. Iranmanesh B, Khalili M, Amiri R, Zartab H Aflatoonian M. Oral manifestations of COVID-19 disease: A review article. Dermatologic Therapy. 2021;34(1):e14578. Go to original source... Go to PubMed...
    29. Criado P R, Ianhez M, Silva de Castro C C, Talhari C, Ramos PM, Miot HA. COVID-19 and skin diseases: results from a survey of 843 patients with atopic dermatitis, psoriasis, vitiligo and chronic urticaria. JEADV. 2022;36:e1-e79. https://doi.org/10.1111/jdv.17635. Go to original source... Go to PubMed...
    30. Donlan AN, Sutherland TE, Marie C, et al. IL-13 is a driver of COVID-19severity. JCI Insight 2021; 6: e150107. https://doi.org/10.1172/jci.insight.150107. Go to original source... Go to PubMed...
    31. Shen WX, Luo RC, Wang JQ, Chen ZS. Features of cytokine storm identified by distinguishing clinical manifestations in COVID-19. Front Public Health. 2021;9:671788 Go to original source... Go to PubMed...
    32. Ocampo-Garza SS, Ocampo-Candiani J, Camela E, Vastarella M, Fabbrocini G, Scalvenzi M, Villani A. Nail changes as manifestation ofsystemic disease in COVID-19infection. J Eur Acad Dermatol. 2021;35:e474-475. Go to original source... Go to PubMed...
    33. Torabi S, Mozdourian M, Rezazadeh R, Payandeh A, Badiee S, Darchini-Maragheh E, et al. Androgenetic alopecia in women and men is not related to COVID-19 infection severity: a prospective cohort study of hospitalized COVID-19 patients. J Eur Acad Dermatol. 2021;35:e553-556. Go to original source... Go to PubMed...

    Return to the content


    Dermatology for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.