Dermatol. praxi. 2025;19(2):64-67 | DOI: 10.36290/der.2025.009
Rosacea and its treatment
- Dermatovenerologické oddělení, Krajská nemocnice Liberec, a. s.
- SKIN CARE Liberec, s. r. o.
Rosacea is a chronic non-infectious inflammatory facial dermatitis that significantly affects the quality of life of patients. The aetiology of rosacea is multifactorial, involving immune dysregulation, vascular changes, skin barrier impairment, skin microbiome changes, and effects of environmental and genetic factors. Provoking factors also play an important role. Clinically, rosacea is typically divided into four subtypes: erythematotelangiectatic, papulopustular, phymatous, and ocular. A more recent approach is classification by phenotypes. The treatment of rosacea requires a comprehensive, individually-tailored approach. Local and systemic therapy, physical methods of treatment, and, in phymatous form, surgical management are available. Proper use of dermocosmetics and avoidance of known provoking factors are integral components of treatment. The treatment is long term and requires a high degree of patient compliance.
Keywords: rosacea, ivermectin, dermocosmetics, prevention.
Accepted: May 13, 2025; Published: May 30, 2025 Show citation
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References
- Saurat JH, Halioua B, Baissac C, et al. Epidemiology of acne and rosacea: A worldwide glo-bal study. J Am Acad Dermatol. 2024 May;90(5):1016-1018. doi: 10.1016/j.jaad.2023.12.038. Epub 2024 Jan 4. PMID: 38184278.
Go to original source... 
Go to PubMed... - Ihrisky, S. A. Rozacea - současný pohled. Available from: https://www.prolekare.cz/.
- Nevoralová Z, Rulcová J, Benáková N. Obličejové dermatózy. Praha: Mladá fronta; 2018.
- Nevoralová Z. Závažná forma růžovky u 32leté pacientky. Dermatol. praxi. 2015;9(3):130-133.
- Pánková R. Rosacea. 2017;11(1):6-11. doi: 10.36290/der.2017.002. Go to original source...
- Dwayebová R. Lokální léčba zánětlivých lézí rosacey u dospělých pacientů. Dermatol. praxi 2018; 12(4): 164-166. Go to original source...
- Rulcová, J. Přehled nejčastějších obličejových dermatóz. I. část. Dermatol. praxi. 2014;8(3):98-101.
- Clanner-Engelshofen BM, Bernhard D, Dargatz S, et al. S2k guideline: Rosacea. J Dtsch Dermatol Ges. 2022 Aug;20(8):1147-1165. doi: 10.1111/ddg.14849. Epub 2022 Aug 5. PMID: 35929658. Go to original source... Go to PubMed...
- Forton FMN. The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea? Dermatol Ther (Heidelb). 2020 Dec;10(6):1229-1253. doi: 10.1007/s13555-020-00458-9. Epub 2020 Oct 23. PMID: 33095403; PMCID: PMC7649190. Go to original source... Go to PubMed...
- Sharma A, Kroumpouzos G, Kassir M, et al. Rosacea management: A comprehensive review. Journal of Cosmetic Dermatology 2022;21:1895-1904. https://doi.org/10.1111/jocd.14816. Go to original source... Go to PubMed...
- Taieb A, Ortonne JP, Ruzicka T, et al. Superiority of ivermectin 1% cream over metronidazo-le 0.75% cream in treating inflammatory lesions of rosacea: a randomized, investigator-blinded trial. British Journal of Dermatology. 2015;172(4):1103-1110. https://doi.org/10.1111/bjd.13408. Go to original source... Go to PubMed...
- Stein L, Kircik L, Fowler J, et al. Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: results of two randomized, double-blind, vehicle-controlled pivo-tal studies. J Drugs Dermatol. 2014 Mar;13(3):316-23. PMID: 24595578.