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MUDr. Radkin Honzák, CSc.

Dermatol. praxi. 2025;19(2):51

Effect of menopause on the skin from the gynaecologist's perspective

doc. MUDr. Peter Koliba, CSc., MUDr. Radek Litvik

Dermatol. praxi. 2025;19(2):53-55 | DOI: 10.36290/der.2025.011

Menopause is a natural biological state when the reproductive period in a woman's life ends. Hormonal changes, particularly a decrease in oestrogen levels, significantly affect all tissues with oestrogen receptors, including the skin. The present article summarizes how menopause affects skin health and describes the currently available therapeutic approaches to managing these changes that are manifested as skin ageing, dryness, loss of collagen, and increased risk of some dermatological conditions. It also explores the options available to mitigate these effects, including hormone replacement therapy (HRT), topical treatments, lifestyle modifications,...

Physiological skin changes during pregnancy

PharmDr. Martina Nováková, PharmDr. Bc. Hana Kotolová, Ph.D.

Dermatol. praxi. 2025;19(2):56-60 | DOI: 10.36290/der.2025.010

During pregnancy, hormonal and other physiological factors cause a number of changes aimed at supporting the development of a new individual. One of the organs affected by these changes is the skin. Physiological manifestations on the skin are expressed in pregnant women to a greater or lesser extent, which is why they burden women to varying degrees and can also affect the psychological aspect during pregnancy. The basis of the correct approach remains differential diagnosis, understanding the mechanism of skin changes and a suitably chosen therapeutic approach focusing on the specifics of pregnant women. The review article points out the most common...

Photoprotection 2025 - characteristic and practical notes

doc. MUDr. Karel Ettler, CSc.

Dermatol. praxi. 2025;19(2):61-63 | DOI: 10.36290/der.2025.013

Ultraviolet radiation from the sun can acutely burn the skin, contribute to the development of photodermatoses, and chronically cause photoaging and skin cancer. Skin phototype represents a complex of natural protection that can be strengthened by behavioral changes, appropriate clothing and sunscreens. Regular use of photoprotection usually does not cause vitamin D deficiency.

Rosacea and its treatment

MUDr. Jana Teplanová

Dermatol. praxi. 2025;19(2):64-67 | DOI: 10.36290/der.2025.009

Rosacea is a chronic non-infectious inflammatory facial dermatitis that significantly affects the quality of life of patients. The aetiology of rosacea is multifactorial, involving immune dysregulation, vascular changes, skin barrier impairment, skin microbiome changes, and effects of environmental and genetic factors. Provoking factors also play an important role. Clinically, rosacea is typically divided into four subtypes: erythematotelangiectatic, papulopustular, phymatous, and ocular. A more recent approach is classification by phenotypes. The treatment of rosacea requires a comprehensive, individually-tailored approach. Local and systemic therapy,...

Autologous progenitor cell transplantation in the treatment of androgenetic alopecia in men and women

MUDr. Samuel Pavlík

Dermatol. praxi. 2025;19(2):68-71 | DOI: 10.36290/der.2025.012

Androgenetic alopecia is the most common cause of hair loss in both men and women. This condition results from genetic predispositions and the influence of androgens, particularly dihydrotestosterone (DHT), which adversely affects hair follicles and leads to their gradual miniaturization. Conventional treatment options include pharmacological therapy (e.g., finasteride or minoxidil) and surgical methods such as hair transplantation. A novel and promising approach is autologous progenitor cell transplantation, a minimally invasive procedure that utilizes the regenerative potential of the patient's own cells. This method has the potential to significantly...

The psychological impact of Hidradenitis Suppurativa: How the disease affects patients' quality of life

MUDr. Júlia Bartková, MBA, MPH, Marie Tormová, MUDr. Gabriela Bakšová

Dermatol. praxi. 2025;19(2):72-74 | DOI: 10.36290/der.2025.008

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that significantly affects patients' quality of life, not only physically but also psychologically. This condition, which affects areas with a high concentration of apocrine glands, is characterized by painful abscesses and sinus tracts. Studies show that patients with HS face an increased risk of psychological issues, particularly depression and anxiety, which can worsen overall well-being and hinder daily functioning. This article focuses on the psychological impact of HS in adult patients, including its effects on their social relationships and overall quality of life. Early diagnosis...

Preschool children successfully treated with dupilumab

MUDr. Michaela Nováková

Dermatol. praxi. 2025;19(2):75-80 | DOI: 10.36290/der.2025.014

Atopic dermatitis (AD) occurs in early childhood in most children, with 80% developing it before the age of 6 years. It is the early childhood experience that significantly affects further psychosocial development. Preschool children learn social skills that involve getting to know peers, communication, listening, and cooperation. Visible manifestations of AD tend to cause stigmatization. They can lead to shyness, low self-esteem, avoidance, and the development of mental disorders. Therefore, adequate and timely treatment is important in children with a severe form of AD, which improves not only the condition of their skin and their mental well-being,...

A case of extensive tinea capitis in a middle-aged woman

MUDr. Kristýna Papajíková, MUDr. Linda Vavříková, MUDr. Martin Tichý, Ph.D.

Dermatol. praxi. 2025;19(2):81-83 | DOI: 10.36290/der.2025.015

Authors describe a 56-year-old woman who developed extensive dermatophytosis of the frontal scalp area. The disease manifested after an episode of severe sideropenic anemia caused by hypermenorrhea due to uterine myomatosis. Systemic therapy with terbinafine led to regression of the skin lesions and complete regrowth of hair.

Hidradenitis suppurativa od teorie k praxi - Zaznělo na 1. konferenci Dermatologie pro praxi České Budějovice, 27. února 2025

MUDr. David Salát

Dermatol. praxi. 2025;19(2):84-86

První zkušenosti s léčbou lebrikizumabem u atopické dermatitidy - Zaznělo na 17. konferenci Dermatologie pro praxi Olomouc, 10. dubna 2025

MUDr. David Salát

Dermatol. praxi. 2025;19(2):88-90