Dermatol. praxi. 2023;17(4):187-192 | DOI: 10.36290/der.2023.035

New treatments for atopic dermatitis

doc. MUDr. Filip Rob, Ph.D.

Dermatovenerologická klinika 2. LF UK a FN Bulovka, Praha

Atopic dermatitis is a chronic inflammatory disease with a very complex pathophysiology, which underlies the wide spectrum of phenotypes of this disease. Therefore for a long time we did not have available a sufficiently effective and at the same time safe therapy for a significant part of patients with severe disease. However, the situation has changed significantly in the last few years. With the advent of biological therapy and, more recently, the advent of JAK inhibitors, the possibilities and success of treatment, especially of severe forms of the disease, have significantly expanded. Currently, there are more than 70 topical and systemic preparations intended for the treatment of atopic dermatitis in various phases of clinical evaluation. In the following years, we can expect further significant improvements in therapeutic options for patients with this disease.

Keywords: atopic dermatitis, treatment, biologic therapy, dupilumab, JAK inhibitors.

Accepted: November 15, 2023; Published: November 21, 2023  Show citation