Dermatol. praxi. 2020;14(3):157-159 | DOI: 10.36290/der.2020.030
Desmoid tumor (deep fibromatosis) of the forearm
- Martinské bioptické centrum, s. r. o., Martin
The author describes a case report of a 56-year old woman, who observed a subcutaneous tumor lesion arising in the left forearm. It clinically appeared as a lipoma. A surgical extirpation of adipose tissue was done, in which a compact tumor mass was identified. It was whitish in color and firm in consistency. Histologically, it consisted of proliferating bland spindle-shaped (myo)fibroblasts with slightly increased mitotic activity. The neoplastic cells were immunohistochemically positive for Faktor XIIIa, α-SMA and calponin and displayed a nuclear reactivity for β-catenin. The tumor margins showed an infiltrative growth pattern. Based on histopathology and immunophenotype, a diagnosis of deep fibromatosis (desmoid tumor) was established. Desmoid tumors of subcutaneous soft tissue are rarely encountered in dermatopathological practice. Although without metastatic potential, they grow aggressively and are accompanied by frequent local recurrences (about 40 % of cases). Therefore, after surgical removal of the tumor, further clinical follow-up of patient is necessary.
Keywords: deep fibromatosis, desmoid tumor, soft tissue tumors.
Published: October 20, 2020 Show citation
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