Dermatol. praxi. 2023;17(4):212-218 | DOI: 10.36290/der.2023.038

Steatocystoma multiplex successfully treated with peroral isotretinoin - a casuistics

MUDr. Zuzana Nevoralová, Ph.D.

Akné poradna, Nemocnice Jihlava, p. o.

A casuistics of a 30-year-old man who was sent to our Acne Clinic because of skin problems lasting for about 8 years is presented. Objectivelly, on the face, neck and trunk many arches were present, the biggest one under the left eyebrow and under the right ear. There were some comedones, papules and small nodules on the trunk. Histological examination of a cyst under the right ear revealed a diagnosis of steatocystoma. Because of concomitant diagnoses acne nodulocystica and steatocystoma multiplex, a treatment with peroral isotretinoin was started with an initial dose 0,25 mg/kg/day, after one month the dose was increased to 0,40 mg/kg/day. Acne was cleared within 6 months. Because of steatocystoma multiplex, the treatment with peroral isotretinoin has been continued. After 20 months of the treatment, the dose of isotretinoin was decreased step by step to a dose 0,075 mg/kg/den (10 mg 4× weekly). The treatment is very well tolerated. For the whole time, local adapalen cream in the evening is applied. In the meantime, the biggest cyst under the left eyebrow was excised with a very good cosmetic result. Cysts on the face, neck and trunk have been slowly diminishing, some have disappeared . Because of steatocystoma multiplex is a chronic disease, a long- term treatment with a low- dose of peroral isotretinoin under regular check-ups has been planned. The patient is very satisfied with the treatment´s effect.

Keywords: steatocystoma multiplex, acne, isotretinoin, long-term treatment.

Accepted: November 15, 2023; Published: November 21, 2023  Show citation