Dermatology for Practice - Latest articles
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Že kočka není pes…Editorial
MUDr. Radkin Honzák, CSc.
Dermatol. praxi. 2026;20(2):51
Význam včasné modifikace průběhu atopické dermatitidy cílenou terapií z pohledu snížení rizika rozvoje komorbiditZaznělo na kongrese
MUDr. Veronika Sommerlíková
Dermatol. praxi. 2026;20(2):93-94
Kolodium forte a léčba virových bradavic: Výsledky postmarketingové, retrospektivní otevřené studieCompany information
Dr. Ing. Petr Behenský, Ing. Milada Bauerová, Mgr. Andrea Fialová
Dermatol. praxi. 2026;20(2):90-92
Self-medication of viral warts: options for keratolytic therapy with salicylic and lactic acids potentiated by herbal componentsAt a glance
PharmDr. Bc. Hana Kotolová, Ph.D.
Dermatol. praxi. 2026;20(2):87-89 | DOI: 10.36290/der.2026.016
Common warts (verruca vulgaris) are a frequent benign viral skin disease caused by human papillomaviruses (HPV). In many cases, they are suitable for self-medication. The mainstay of home treatment consists of keratolytic preparations containing salicylic acid and lactic acid, most commonly formulated as collodion solutions. This article summarizes the mechanisms of action of these agents, the principles of the collodion dosage form, recommendations for proper application, the indications and limitations of self-treatment, and an overview of products available on the Czech market.
The fractional 1927-nm thulium laser as a treatment modality for actinic keratosisCase report
MUDr. Kevin Machů
Dermatol. praxi. 2026;20(2):84-86 | DOI: 10.36290/der.2026.015
This paper presents a case report of a 45-year-old patient in whom multiple actinic keratoses of the scalp consistent with field cancerization were detected during a total body dermoscopic examination. At the same time, a nodular basal cell carcinoma on the right shoulder was identified. Considering the patient's preferences, treatment with a 1927 nm fractional thulium laser was chosen. The first session was well tolerated by the patient and led to a marked improvement in both clinical and dermoscopic findings. The article further discusses the use of the fractional thulium laser in the treatment of actinic keratoses and its role among other...
Carcinoma en cuirasse: cutaneous metastases as a manifestation of breast cancer relapseCase report
MUDr. Monika Baláž, MUDr. Martin Tichý, Ph.D., MUDr. Patrik Flodr, Ph.D.
Dermatol. praxi. 2026;20(2):81-83 | DOI: 10.36290/der.2026.014
Carcinoma en cuirasse is a rare form of cutaneous metastases, most commonly associated with breast cancer. It is clinically manifested as diffuse sclerodermiform induration of the skin. We present a case of a 68-year-old female patient with a history of triple-negative breast cancer who developed a palpably firm lesion in the mastectomy scar site after more than three years of remission. Histopathological examination confirmed a metastatic process congruous with carcinoma en cuirasse. The case highlights the importance of early biopsy in newly developed induration in a mastectomy scar and the dermatologist's role in diagnosing local recurrence.
Food allergens and their relevance in dermatological practiceInterdisciplinary overviews
MUDr. Mojmír Račanský
Dermatol. praxi. 2026;20(2):78-80 | DOI: 10.36290/der.2026.013
Dietary allergens are a primary trigger for allergic and pseudoallergic reactions. The skin is among the most commonly affected organs, involved in early IgE-mediated responses as well as in non-IgE-mediated and mixed immunopathological mechanisms. The clinical manifestations include acute urticaria, angioedema, contact urticaria, flare-ups of atopic dermatitis, and chronic itching. In addition to naturally occurring food allergens, food additives and preservatives play a significant role, as they can cause pseudoallergic reactions - especially in patients with chronic urticaria. Diagnosis relies on a detailed medical history, targeted laboratory tests,...
Inhibitors of Bruton's tyrosine kinase in the treatment of chronic spontaneous urticariaReview articles
MUDr. Tomáš Balner
Dermatol. praxi. 2026;20(2):74-77 | DOI: 10.36290/der.2026.012
Chronic spontaneous urticaria (CSU) is a disease with a substantial impact on quality of life, and in a proportion of patients it remains inadequately controlled despite maximum‑dose second‑generation H1 antihistamines and treatment with omalizumab. The updated international CSU treatment algorithm includes remibrutinib, alongside omalizumab and dupilumab, as a second‑line add‑on therapy to second‑generation antihistamines. This article reviews the mechanism of action of BTK inhibitors, key clinical data on the new generation of Bruton's tyrosine kinase inhibitors, and practical aspects of their use (safety, vaccination,...
Non-melanoma skin cancers: part I. basal cell carcinoma and squamous cell carcinomaReview articles
MUDr. Edita Marvanová
Dermatol. praxi. 2026;20(2):65-73 | DOI: 10.36290/der.2026.011
Malignant skin tumors represent a heterogeneous group consisting of melanoma as a distinct entity and the so-called non-melanoma skin cancers (NMSC). This classification is based on the different biological behaviour of individual tumors, which determines distinct therapeutic approaches. The main representatives of NMSC are basal cell carcinoma (75-80 % of NMSC) and squamous cell carcinoma (20 % of NMSC). Less common skin malignancies include Kaposi sarcoma, dermatofibrosarcoma protuberans, Merkel cell carcinoma, extramammary Paget disease, and adnexal carcinomas. Cutaneous metastases from internal malignancies may also occur. The aim of this article...
Trends in acne treatment in adolescentsReview articles
MUDr. Anna Hrazdírová
Dermatol. praxi. 2026;20(2):60-64 | DOI: 10.36290/der.2026.010
Acne is one of the most common dermatological conditions of adolescence, significantly affecting the quality of life of patients. Current trends in treatment emphasize the early use of topical retinoids, the use of fixed-dose combinations, earlier initiation of oral isotretinoin, and the limited use of antibiotic therapy. Dermocosmetic care is an important part of the treatment as well. Minimally invasive aesthetic procedures are increasingly used in the management of acne sequelae, particularly scars and post-inflammatory pigmentation. The treatment should be individualized, simple, and targeted not only at active manifestations of the disease, but...
Differential diagnosis and management of lower limb edema in dermatological practiceReview articles
MUDr. Natálie Michalík, MUDr. Silvie Rafčíková, MBA
Dermatol. praxi. 2026;20(2):54-59 | DOI: 10.36290/der.2026.009
Lower limb edema represents a common clinical symptom with a wide number of etiologies, ranging from chronic venous insufficiency and lymphedema to systemic diseases or life-threatening diagnoses like deep vein thrombosis. For the dermatologist, correct differential diagnosis based on patient history, physical examination, and, in indicated cases, imaging modalities is crucial. This article presents a clear diagnostic algorithm and management of lower limb edema in routine dermatological practice and specifically focuses on the treatment of venous and lymphatic edema, which is based on lifestyle measures, compression therapy, venoactive drugs, and...
Výzvy dermatovenerologieEditorial
doc. MUDr. Miloslav Salavec, CSc.
Dermatol. praxi. 2026;20(1):3
Id reaction following impetiginized contact dermatitisCase report
MUDr. Anna Hrazdírová
Dermatol. praxi. 2026;20(1):36-38 | DOI: 10.36290/der.2026.001
An id reaction (autosensitization dermatitis) is a generalized, immunologically mediated skin response that develops secondarily as a result of a distant primary focus. It typically occurs in patients with eczema or fungal and bacterial skin infections, yet in clinical practice it is often overlooked or misdiagnosed. Successful resolution depends on adequate treatment of the primary lesion together with symptomatic management of the id reaction. We present the case of a 12-year-old patient with impetiginized contact dermatitis of the left knee following trauma, complicated by the development of an id reaction on the trunk, neck and axillary regions....
Dermatitis artefactaCase report
MUDr. Blanka Pinková, Ph.D.
Dermatol. praxi. 2026;20(1):33-35 | DOI: 10.36290/der.2026.004
Dermatitis artefacta is a relatively rare disease, the incidence of which has been increasing in recent years. With the growing media coverage of various activities, various methods that were previously unavailable or less accessible are becoming increasingly available. We are therefore finding manifestations in increasingly younger patients, not only in adolescents but also in children. Therapy is difficult, requiring long-term cooperation of the patient, but also the family with psychologists. the family and psychologists.
Morbus Favre-Racouchot successfully treated with a topical retinoid and manual expression: a case reportCase report
MUDr. Barbara Pásztorová, MUDr. Zuzana Nevoralová
Dermatol. praxi. 2026;20(1):30-32 | DOI: 10.36290/der.2026.005
Morbus Favre-Racouchot (MFR), also known as nodular elastosis, is a chronic skin disease caused by long-term exposure to sunlight. It is characterized by the presence of comedones and cysts. This article presents a case report of a 62-year-old patient with extensive facial macrocomedones lasting for more than 40 years. Long-term treatment with topical adapalene and manual expression led to a reduction of skin lesions by more than 90%. This case demonstrates that above mentioned treatment can be very effective.
Challenges in the clinical diagnosis of scabiesCase report
MUDr. Paulína Cabalová
Dermatol. praxi. 2026;20(1):26-29 | DOI: 10.36290/der.2026.006
Scabies remains a relevant infectious disease with cyclic peaks in epidemics, which are currently developing even in conditions of high hygienic standards. Diagnosis is often complicated by atypical manifestations or secondary changes. Treatment should be comprehensive and include not only the patient but also their immediate surroundings, along with proper education regarding transmission methods and epidemiological measures. Early diagnosis is crucial, as long-term misdiagnosis leads to delays in treatment and an increased risk of disease transmission. The author describes a case of a patient with recurrent episodes of scabies, illustrating why despite...
Vitamins - physiological functions and signs of deficiency on the skinInterdisciplinary overviews
PharmDr. Bc. Hana Kotolová, Ph.D., PharmDr. Veronika Krupicová, PharmDr. Tomáš Hammer, Ph.D., PharmDr. Martina Nováková
Dermatol. praxi. 2026;20(1):20-25 | DOI: 10.36290/der.2026.007
Vitamins are essential dietary components necessary for the proper growth, development, and functioning of the entire organism. The importance of individual vitamins within the body is interconnected. Vitamins help maintain the balance between catabolic and anabolic processes by activating and linking different metabolic pathways. Currently, in development countries, symptoms of avitaminosis are encountered only rarely, whereas signs of certain hypovitaminoses are diagnosed much more frequently. Vitamin deficiency can manifest through various dermatological symptoms, ranging from changes in the structure and function of the epidermis to impaired healing...
Direct immunofluorescence in dermatology and dermatopathologyReview articles
MUDr. Miroslav Důra, Ph.D.
Dermatol. praxi. 2026;20(1):15-19 | DOI: 10.36290/der.2026.002
Examination of the presence of tissue-bound antibodies, complement components, or fibrinogen by direct immunofluorescence plays an indispensable role in dermatology and dermatopathology. For several diagnoses, particularly autoimmune bullous dermatoses, it even constitutes a diagnostic criterion. The following text focuses on the principles of this examination, its indications, benefits, and limitations. The immunofluorescence patterns of individual dermatoses are discussed. Practical information regarding proper specimen collection and transport is also included.
Dermatovenerological specifics of care for transgender patientsReview articles
MUDr. Kevin Machů
Dermatol. praxi. 2026;20(1):11-14 | DOI: 10.36290/der.2026.003
Care of transgender patients represents a complex and multidisciplinary field encompassing medical, dermatological, surgical, and psychosocial aspects. This article focuses on specific issues of dermatological care in transgender individuals in the context of hormone therapy and surgical transition. The effects of androgens and estrogens on the skin and skin appendages are described, including the occurrence of acne, alopecia, and changes in hair growth. Attention is paid to therapeutic options and challenges in the management of these conditions, including isotretinoin therapy and issues related to contraception. Further topics discussed include epilation...
Chronic hand eczema and its treatment in dermatological practiceReview articles
MUDr. Linda Vavříková, MUDr. Martin Tichý, Ph.D.
Dermatol. praxi. 2026;20(1):6-10 | DOI: 10.36290/der.2026.008
Chronic hand eczema is a multifactorial disease that significantly affects quality of life and work ability. It is common disease in general population and especially in certain professions. We focus on the classification of eczema based on etiology and morphological features, as well as its examination and therapy.
Zaznělo na 31. národním dermatologickém kongrese v Brně, 31. 10. – 1. 11. 2025.
Bimekizumab: dvojitý zásah v léčbě psoriatického onemocněníZaznělo na kongrese
MUDr. Zuzana Zafarová
Dermatol. praxi. 2025;19(4):192-198
Cítím s tebou aneb úvaha o empatiiEditorial
MUDr. Radkin Honzák, CSc.
Dermatol. praxi. 2025;19(4):139
Zaznělo na 31. národním dermatologickém kongrese v Brně, 31. 10. - 1. 11. 2025.
Zkušenosti s tildrakizumabem v klinické praxi - pohled českého a moravského centraZaznělo na kongrese
MUDr. Zuzana Zafarová
Dermatol. praxi. 2025;19(4):188-191
Care for children's skin in winterAt a glance
doc. MUDr. Karel Ettler, CSc.
Dermatol. praxi. 2025;19(4):185-187 | DOI: 10.36290/der.2025.033
Winter period presents challenging conditions for human skin, especially due to frequent temperature changes, low relative humidity and cold wind. The skin is more susceptible to dehydration, irritation and inflammatory reactions during this period. The article deals with the physiological reactions of the skin to cold and frost, recommendations for the treatment and prevention of skin problems.
A comprehensive look at skin hyperpigmentationCosmetic dermatology spot
MUDr. Lucia Mansfeldová
Dermatol. praxi. 2025;19(4):178-184 | DOI: 10.36290/der.2025.032
There is a great variability in human skin color worldwide, from very light skin of the Celtic type (phototype I) to dark skin tones in sub-Saharan Africa (phototype V-VI). We also encounter a very wide range of different pigmentation disorders, from hypopigmentation to hyperpigmentation. In general, people, regardless of their phototype, are very often plagued by localized accumulated hyperpigmentation, which is why this issue is one of the most common reasons for consulting dermatologists. Skin hyperpigmentation causes significant psychological stress, discomfort and social stigmatization for many (it is reported in up to approximately 84% of those...
Aesthetic treatment combinationsCosmetic dermatology spot
MUDr. Kevin Machů
Dermatol. praxi. 2025;19(4):173-176 | DOI: 10.36290/der.2025.031
Aesthetic treatment combinations are nowadays an integral part of dermatological practice. A properly chosen strategy allows to achieve natural and long-lasting results, as individual techniques target different skin layers and complement one another. The article focuses on how to combine and time botulinum toxin, dermal fillers, lasers, radiofrequency microneedling, threads, and chemical peels in order to achieve a synergistic effect while minimizing the risk of complications. Also discussed is the use of combination protocols in rosacea, acne, scars, pigment spots as well as in treating and preventing skin ageing. The key to success is an individual...
Experience with treating rosacea with Soolantra creamCase report
MUDr. Hana Janatová
Dermatol. praxi. 2025;19(4):168-172 | DOI: 10.36290/der.2025.030
Rosacea is a chronic inflammatory skin condition that primarily affects the central area of the face and can significantly impact patients' quality of life. Common symptoms include redness, papules, pustules, and often a burning or itching sensation. One of the modern topical treatment options is Soolantra cream, which contains ivermectin - a compound with anti-inflammatory and antiparasitic properties. This article presents three case reports of patients with different forms of rosacea who were successfully treated with Soolantra.
The importance of microbiological findings in non-healing wounds in the clinical practiceCase report
MUDr. Daniel Wolny, doc. MUDr. Ladislav Štěpánek, Ph.D., prof. MUDr. Dagmar Horáková, Ph.D.
Dermatol. praxi. 2025;19(4):162-166 | DOI: 10.36290/der.2025.029
Introduction: Non-healing wounds are a major medical and socioeconomic issue. Microbiological agents are the key factor in their pathogenesis, affecting not only the rate, but the very possibility of healing. The aim of the study was to analyze the spectrum of microorganisms isolated from non-healing wounds and to assess their effect on the duration and success of healing. Methods: This observational ambispective study enrolled patients with chronic wounds treated at the Outpatient Department of Surgery of the Military Hospital Olomouc between August 2021 and September 2023. In patients with signs of infection, wound swabs were taken using the Levine...
Non-melanoma skin cancers: current insights into diagnosis, prevention, and treatmentReview articles
MUDr. Júlia Bartková, MBA, MPH, Marie Tormová, Janusz Rucki, Sandra Harásková, Soňa Hrižová, MUDr. Dušana Selecká, MUDr. Gabriela Bakšová
Dermatol. praxi. 2025;19(4):156-161 | DOI: 10.36290/der.2025.028
Non-melanoma skin cancers (NMSC) represent the most frequently diagnosed malignancies in developed countries, with a globally rising incidence. This review article summarizes the main types of NMSC - basal cell carcinoma, squamous cell carcinoma, and Merkel cell carcinoma - with a focus on their epidemiology, risk factors, diagnosis, treatment, and preventive strategies. Particular attention is given to primary and secondary prevention, including current research on chemoprevention agents such as nicotinamide, vitamin D, and celecoxib. The article also discusses the importance of early detection, surgical and non-surgical treatment approaches, and...
Tuberculosis cutis luposa - Lupus vulgarisReview articles
doc. MUDr. Jarmila Rulcová, CSc.
Dermatol. praxi. 2025;19(4):153-155 | DOI: 10.36290/der.2025.027
Lupus vulgaris is the most common form of cutaneous tuberculosis. It is a chronic and slowly progressive disease. This form of cutaneous tuberculosis is found in individuals with moderate immunity and a strong tuberculin sensitivity. A characteristic feature of lupus vulgaris is an extremely chronic course with slow but steady growth of the lesions over a period of many years, or even decades.